时间:2026-05-23 15:04:02 来源:网络整理编辑:休閑
Calmer. Happier. Way more productive.That may sound like the first line of a Radiohead song. In fact
Calmer. Happier. Way more productive.
That may sound like the first line of a Radiohead song. In fact, it's how author Ayelet Waldman felt after trying a tiny dose of LSD every third day for a month.
SEE ALSO:A guide to marijuana microdosing: How tiny hits could be the future of weedWaldman's curious experiment is the subject of A Really Good Day: How Microdosing Made a Mega Difference in My Mood, My Marriage and My Life, a highly readable nonfiction diary released this month by Knopf.
The book makes a compelling case for why acid should be decriminalized like marijuana in several states. Both drugs have medical benefits, and neither have ever been shown to kill a human being at any dose. (Those stories from the 1970s about acid droppers jumping out of windows because they thought they could fly? An urban legend largely spread by one TV presenter.)

More importantly for the reader, this advocacy comes in the context of a funny and relatable real-life soap opera. Waldman is not shy in discussing her personal life. We get the good, the bad and the ugly in her relationship with her four kids and spouse, the Pulitzer Prize-winning novelist behind The Amazing Adventures of Kavalier and Clay, Michael Chabon.
Waldman and Chabon fret about their kids, go through heartbreakingly passive-aggressive sessions of couples therapy, and have knock-down, drag-out fights about emptying the dishwasher, the placement of a sofa and the amount of defunct audio equipment in the shed.
Celebrity authors: they're just like us!
SEE ALSO:Stephen King and 600 more U.S. authors come out against TrumpSeriously, though, if you've ever struggled with depression, insomnia, low self-esteem, the legacy of emotionally distant parents, or any kind of persistent bodily pain (in her case, a frozen shoulder), you will identify with Waldman's inner thought process, and be amused by her dark sense of humor about the whole thing. The writing is clear, and it sparkles.
As the diary opens, she's desperate. Bipolar disorder and perimenopause have done a number on her brain, and no drug in the alphabet soup provided by Big Pharma is helping. Not even meditation or years of therapy can shift her moods.
Waldman is cranky, miserable, tormented and tormenting her family in return, and can only write in occasional manic bursts.
"Do you think you might need an SSRI today?" Chabon asks in the most neutral tone he can manage. "I did my part by neither defenestrating nor decapitating him," Waldman writes.
Then she stumbles on the work of James Fadiman, a psychologist who for years has been crowdsourcing a self-reported study of LSD microdosing. (Because the government has kept acid on Schedule A, no regular scientific study is likely any time soon.)
An anonymous academic calling himself Lewis Carrol leaves a blue vial of liquid LSD in her mailbox
His recommended protocol: take ten micrograms, wait two days, take ten more micrograms, repeat. Observe your responses and keep a daily record. (Ten micrograms is about 1/10th what you'd need to even start to feel like you're tripping.)
Waldman, a straitlaced former attorney, has never taken the stuff before. She is wary, anxious, and very bad at soliciting drugs. But she also lives in Berkeley, so it doesn't take too many calls before an anonymous elderly academic calling himself Lewis Carrol leaves a blue vial of liquid LSD in her mailbox.
She employs a testing kit on it before using, naturally.
In her diary, she tracks her physical sensations, her mood, her sleep levels, the amount of conflict she creates. On her microdose days, she observes herself being a little more chatty and "up" than normal, but few other discernible differences.
It's the "transition day" -- the day after the microdose -- when Waldman generally finds the most benefits. Suddenly she's writing like a demon, and good stuff too. She's filled with a sense of peace and love and discipline. The pain in her shoulder largely vanishes. Sleep comes easier.
SEE ALSO:Doctors discover why stressed out people have more heart attacksIntra-family conflict doesn't go away -- there's one particularly panicky episode when she fears her eldest in college has gotten a tattoo, based on a misunderstood Instagram post -- but it becomes easier to resolve.
At the end of the month, with the last drop of the vial approaching and Lewis Carrol nowhere to be found, Waldman tries to solicit more, only to panic when her new source tries to sell her precisely the amount that would raise the federal crime from possession to distribution. A former attorney for drug offenders, she knows all about entrapment.
Absent that incident, Waldman says, she'd still be microdosing today. Read her AMA on Reddit for more on that.
Waldman is far from alone in reporting these kinds of results; there's a whole underground network of microdosers out there. Albert Hoffman, the Swiss chemist who accidentally invented LSD in the first place, was microdosing well into his 80s, and died at 102.
We still don't know exactly how acid works, or why it should have such a positive effect on many people at such minuscule doses. (Researchers have only just mapped out how the LSD molecule attaches to receptors in the brain, in a study published Thursday.)
We do know that more study is needed -- and that if Attorney General nominee Jeff "Good people don't smoke marijuana" Sessions ends up running the DEA, that isn't likely any time this decade.
TopicsBooks
Teacher absolutely nails it with new homework policy2026-05-23 15:03
千麵人生王一博:從一張點卡到為夢營業2026-05-23 15:03
景甜亮相上海品牌活動 夢幻銀熠氣場全開2026-05-23 15:00
【波盈足球】 世足黑馬摩洛哥1比0勝葡萄牙 非洲球隊破天荒闖入4強 ( 摩洛哥,葡萄牙 )2026-05-23 14:38
MashReads Podcast: What makes a good summer read?2026-05-23 14:24
愛奇藝《潮流合夥人》今晚8點上線 聚焦潮流賽道打造新消費場景2026-05-23 14:04
1月10日《士兵順溜:兵王爭鋒》血性而來!2026-05-23 13:59
馬常旭首張個人音樂專輯《不會再欺騙我》發布2026-05-23 13:52
Chinese gymnastics team horrifies crowd with human jump rope2026-05-23 13:51
偶像駕到!《青春有你》人氣學員田島入駐虎牙,開啟直播首秀2026-05-23 13:20
Tyler, the Creator helped Frank Ocean celebrate 'Blonde' release in a delicious way2026-05-23 14:47
王大陸都愛玩的機器人 ,為什麽值得一試2026-05-23 14:47
泰國達美傾情讚助少兒春晚暨亞洲小姐總決賽,展望2020 !2026-05-23 14:43
重磅!台鈴與東方衛視達成戰略合作 獨家冠名王牌綜藝《親愛的 ,來吃飯》!2026-05-23 14:43
Pole vaulter claims his penis is not to blame2026-05-23 14:40
2019歡樂深活節,一場歡樂青年的時髦狂歡即將來襲!2026-05-23 14:21
當經典遇上新聲!《主持人大賽》為老牌節目注入青春活力2026-05-23 13:53
來自冰島的小精靈—vivo S5開箱體驗,我被它的自拍原地圈粉了2026-05-23 13:19
J.K. Rowling makes 'Harry Potter' joke about Olympics event2026-05-23 12:46
當廣場舞遇到音樂劇,大麥也變得愛玩又會玩了?2026-05-23 12:38