时间:2026-04-14 13:35:57 来源:网络整理编辑:熱點
In a world awash in antibiotics, dangerous infections are getting even harder to fight. The problem?
In a world awash in antibiotics, dangerous infections are getting even harder to fight.
The problem? Bacteria are outsmarting the drugs meant to wipe them out at a faster pace than new antibiotics can be discovered and produced.
To address the growing crisis of antibiotic resistance, global health officials on Monday listed a dozen antibiotic-resistant "priority pathogens" that pose the greatest threats to human health.
SEE ALSO:This bacteria is getting harder for kids to fightThe first-of-its-kind list is meant to steer public and private research dollars toward developing new antibiotics for these particular families of bacteria, the World Health Organization (WHO) said. The announcement is also designed to push public agencies to support more research by pharmaceutical companies, which currently lack financial incentives to develop new drugs aimed at rare, but deadly, superbugs.
"Governments and industry must work very closely on this if we are to find new weapons to fight growing antimicrobial resistance," Marie-Paule Kieny, WHO's assistant director-general for health systems and innovation, said Monday on a call with reporters.
Via Giphy"It's very important to start now, as quickly as possible, in order to have in three, five, 10 years, the antibiotics that we need," she said.
Drug-resistant bacteria infect millions of people around the world, though experts on the press call said it's difficult to know precisely how many people are affected each year, or how many infections result in death.
In simple terms, the main cause of this scary trend is that we've been taking too many antibiotics and using them widely to grow livestock for food in mainly developed countries.
Doctors might prescribe the pills -- or patients demand them -- to treat illnesses that aren't actually bacterial infections. The enormous use of antibiotics in the livestock industry is also spreading drug-resistant bacteria through our food supply.
Credit: world health organizationThe list focuses on "gram-negative bacteria" that are resistant to multiple antibiotics and can pass on genetic material to other bacteria, allowing those to develop drug resistance as well.
Gram-negative bugs most frequently affect a person's intestinal tract, which can lead to severe and life-threatening bloodstream infections and pneumonia -- particularly among elderly people in nursing homes and hospitals. The bacteria can also contaminate medical equipment, such as blood catheters and ventilators.
"This has been a major challenge for modern medicine," Kieny said. "These bacteria are really spreading very frequently in health care facilities."
They're also far more difficult and expensive to study compared to "gram-positive bacteria," which tend to affect the nose and skin of a healthy individual.
Antibiotics can be too much of a good thing.Credit: JOE RAEDLE/Getty ImagesThat's why private pharmaceutical companies and public health agencies have tended to invest more time and money in developing solutions for gram-positive bacteria, Nicola Magrini, a WHO scientist for innovation, access and use of essential medicines, said.
He said the WHO researchers hoped to send a "strong message" to the public health and pharmaceutical communities that more investment is needed for these 12 priority pathogens.
The WHO list is divided into three categories based on the urgency of need for new antibiotics.
WHO's "priority pathogens" list
Priority 1: Critical
1. Acinetobacter baumannii, carbapenem-resistant2. Pseudomonas aeruginosa, carbapenem-resistant3. Enterobacteriaceae, carbapenem-resistant, ESBL-producing
Priority 2: High
4. Enterococcus faecium, vancomycin-resistant5. Staphylococcus aureus, methicillin-resistant, vancomycin-intermediate and resistant6. Helicobacter pylori, clarithromycin-resistant7. Campylobacterspp., fluoroquinolone-resistant8. Salmonellae, fluoroquinolone-resistant9. Neisseria gonorrhoeae, cephalosporin-resistant, fluoroquinolone-resistant
Priority 3: Medium
10. Streptococcus pneumoniae, penicillin-non-susceptible11. Haemophilus influenzae, ampicillin-resistant12. Shigellaspp., fluoroquinolone-resistant
Bacteria in the "critical" group include multi-drug resistant bacteria that can withstand the use of antibiotics known as carbapenems, as well as third-generation cephalosporins. These are currently the antibiotics of last resort.
The "high" and "medium" priority bacteria include other increasingly drug-resistant bacteria that cause more common diseases, including gonorrhea and food poisoning caused by salmonella.
WHO developed its list together with the division of infectious diseases at the University of Tübingen in Germany.
"New antibiotics targeting this priority list of pathogens will help to reduce deaths due to resistant infections around the world," Evelina Tacconelli, a professor at the University of Tübingen who helped develop the list, said in a press release.
"Waiting any longer will cause further public health problems and dramatically impact on patient care," she said.
Tyler, the Creator helped Frank Ocean celebrate 'Blonde' release in a delicious way2026-04-14 13:27
鉑爵旅拍怎麽樣?疫後首部國產電影定檔7.20 ,鉑爵旅拍打造旅拍電影質感2026-04-14 13:11
《摩天大樓》今晚開播郭濤楊子姍成師徒 Angelababy第一集“領盒飯”2026-04-14 12:59
鼎和文創出品主旋律電影《黎明之戰》開機 打造正能量愛國大片2026-04-14 12:55
Donald Trump's tangled web of Russian influence2026-04-14 12:25
《神奇女俠2》發布多張無水印劇照,複古風濃鬱,一起穿越回到19842026-04-14 12:10
史上最長片名 《變化中的中國·生活因你而火熱》定檔11月22日2026-04-14 12:10
電影《非常替身》好消息不斷,引發媒體關注2026-04-14 11:17
The Weeknd teases new music in Instagram post2026-04-14 11:03
林允自曝錄《我家那閨女》感覺很恐怖 :平時已經被窺視得不少了!2026-04-14 11:01
PlayStation Now game streaming is coming to PC2026-04-14 13:26
《星際穿越》複映票房破億 諾蘭三連助力影院重啟2026-04-14 13:26
電影《封神三部曲》年輕演員群像曝光 完美詮釋中國古典男性氣質2026-04-14 13:25
《奇門遁甲》重磅來襲 罪惡溫晁變身無敵天師2026-04-14 12:16
Metallica to seek and destroy your eardrums with new album this fall2026-04-14 12:05
《抵達之謎》謎底揭曉 野性顧璿與李現搭檔共赴肆意青春2026-04-14 12:01
《天網狙擊》最新消息2026-04-14 11:46
《非常替身》劇組劇本圍讀,用心造精品2026-04-14 11:36
'Rocket League' Championship Series Season 2 offers $250,000 prize pool2026-04-14 11:20
不愛武藝愛廚藝 《九指神丐》上映看點多2026-04-14 10:53